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Anti-MeV Phosphoprotein Polyclonal Antibody|抗MeV磷蛋白多克隆抗体(靶标:麻疹病毒磷蛋白)

  • 货号:RB9TVK796014
  • 价格:面议
  • 点击:249

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Measles virus
靶标P/V, Phosphoprotein, Protein P
免疫原E. coli - derived recombinant MeV Phosphoprotein (Gly304-Leu377).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9WMB4
背景信息

Phosphoprotein is a ~53 kDa protein. Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Also plays a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication. The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place.

1. Guseva, S. et al. (2020) Science advances 6, eaaz7095. PMID: 32270045
备注For research use only
【仅供科学研究使用】

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