Anti-Mouse CD63/LAMP3 Polyclonal Antibody|抗小鼠CD63/LAMP3多克隆抗体(靶标：小鼠CD63分子/LAMP3)
- 货号：RB9TMY592014
- 价格：面议
- 点击：423
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat |
| 靶标 | CD63, CD63 antigen, Cd63 |
| 免疫原 | E. coli - derived recombinant Mouse CD63/LAMP3 (Ala103-Ile203). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P41731 |
| 背景信息 | CD63 antigen (LAMP3) is a ~25 kDa protein. Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. |
| 备注 | For research use only |
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