当前位置:首页>产品中心>单抗/多抗>Anti-Mouse CD63/LAMP3 Polyclonal Antibody|抗小鼠CD63/LAMP3多克隆抗体(靶标:小鼠CD63分子/LAMP3)

Anti-Mouse CD63/LAMP3 Polyclonal Antibody|抗小鼠CD63/LAMP3多克隆抗体(靶标:小鼠CD63分子/LAMP3)

  • 货号:RB9TMY592014
  • 价格:面议
  • 点击:458
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Rat
靶标CD63, CD63 antigen, Cd63
免疫原E. coli - derived recombinant Mouse CD63/LAMP3 (Ala103-Ile203).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P41731
背景信息

CD63 antigen (LAMP3) is a ~25 kDa protein. Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes.

备注For research use only
【仅供科学研究使用】

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