| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | IL-13, Il-13, Il13, Interleukin-13, T-cell activation protein P600 |
| 免疫原 | E. coli - derived recombinant Mouse IL13 (Ser26-Phe131). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P20109 |
| 背景信息 | Interleukin-13 (IL13) is a ~14 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B. 1. Finkelman, FD. et al. (2004) Immunological reviews 201, 139-55. PMID: 15361238 2. Zhang, M. et al. (2021) Journal of immunology (Baltimore, Md. : 1950) 207, 3070-3080. PMID: 34789557 3. Mayer, JU. et al. (2021) Nature immunology 22, 1538-1550. PMID: 34795444 4. Takeda, K. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 3220-2. PMID: 8871614 5. Duffen, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1347-1359. PMID: 29305434 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 痢疾志贺氏菌单克隆抗体 | 7667 |
| 沙门氏菌单克隆抗体 | 7504 |
| 乙型副伤寒沙门氏菌单克隆抗体 | 8096 |
| A族链球菌单克隆抗体 | 7742 |
| 甲型副伤寒沙门氏菌单抗 | 7503 |
| 麻疹病毒单克隆抗体 | 7646 |
| HBeAg单克隆抗体 | 7667 |
| 新型冠状病毒(SARS-COV-2)NP蛋白单克隆抗体 | 7141 |
| 呼吸道腺病毒单克隆抗体 | 7967 |
| 大肠杆菌单克隆抗体 | 7732 |
| LP-PLA2单克隆抗体 | 7703 |
| NT-PROBNP单克隆抗体 | 7403 |
| 半乳糖凝集素3单克隆抗体 | 7445 |
| D二聚体单克隆抗体 | 7541 |
| 肌钙蛋白单克隆抗体 | 7726 |
| 肌红蛋白单克隆抗体 | 7607 |
| AAT单克隆抗体 | 7526 |
| 人SAA单克隆抗体 | 7411 |
| 黏病毒抗性蛋白A单克隆抗体 | 7617 |
| 降钙素原单克隆抗体 | 7288 |