| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | IL-13, Il-13, Il13, Interleukin-13, T-cell activation protein P600 |
| 免疫原 | E. coli - derived recombinant Mouse IL13 (Ser26-Phe131). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P20109 |
| 背景信息 | Interleukin-13 (IL13) is a ~14 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B. 1. Finkelman, FD. et al. (2004) Immunological reviews 201, 139-55. PMID: 15361238 2. Zhang, M. et al. (2021) Journal of immunology (Baltimore, Md. : 1950) 207, 3070-3080. PMID: 34789557 3. Mayer, JU. et al. (2021) Nature immunology 22, 1538-1550. PMID: 34795444 4. Takeda, K. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 3220-2. PMID: 8871614 5. Duffen, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1347-1359. PMID: 29305434 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6375 |
| 多菌灵/阿苯达唑二合一单抗 | 6469 |
| 三氯噻嗪单抗 | 6558 |
| 吡唑醚菌酯单抗 | 6810 |
| 烯酰吗啉单抗 | 6684 |
| 抑霉唑单抗 | 6324 |
| 恶醚唑(苯醚甲环唑)单抗 | 6496 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6507 |
| 辛硫磷单抗 | 6606 |
| 多效唑单抗 | 6498 |
| 对硫磷单抗 | 6688 |
| 丙溴磷单抗 | 6740 |
| 戊唑醇单抗 | 6750 |
| 莠去津单抗 | 6595 |
| 灭蝇胺单抗 | 6265 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6542 |
| 2.4-二氯苯氧乙酸单抗 | 6381 |
| 甲基对硫磷单抗 | 6447 |
| 左旋咪唑单抗 | 6409 |
| 三唑磷单抗 | 6501 |