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Anti-Mouse CD13/ANPEP Polyclonal Antibody|抗小鼠CD13/ANPEP多克隆抗体(靶标:小鼠丙氨酰氨基肽酶/CD13)

  • 货号:RB9TMB650014
  • 价格:面议
  • 点击:490

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse
靶标AP-M, AP-N, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, Anpep, CD13, EC:3.4.11.2, Lap-1, Lap1, Membrane protein p161, Microsomal aminopeptidase, mAPN
免疫原E. coli - derived recombinant Mouse CD13/ANPEP (Thr79-Glu285).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P97449
背景信息

Aminopeptidase N (CD13/ANPEP) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity.

1. Larsen, SL. et al. (1996) The Journal of experimental medicine 184, 183-9. PMID: 8691132
2. Fairweather, SJ. et al. (2012) The Biochemical journal 446, 135-48. PMID: 22677001
备注For research use only
【仅供科学研究使用】

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