Anti-Mouse IL9 Polyclonal Antibody|抗小鼠IL9多克隆抗体(靶标：小鼠白细胞介素9)
- 货号：RB9TMB771014
- 价格：面议
- 点击：725
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | Cytokine P40, IL-9, Il9, Interleukin-9, T-cell growth factor P40 |
| 免疫原 | E. coli - derived recombinant Mouse IL9 (Gln19-Pro144). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P15247 |
| 背景信息 | Interleukin-9 (IL9) is a ~16 kDa protein. Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites. Affects intestinal epithelial permeability and adaptive immunity. In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells. Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG. Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs. 1. Townsend, JM. et al. (2000) Immunity 13, 573-83. PMID: 11070175 2. Elyaman, W. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 12885-90. PMID: 19433802 3. Khan, WI. et al. (2003) Infection and immunity 71, 2430-8. PMID: 12704113 4. Druez, C. et al. (1990) Journal of immunology (Baltimore, Md. : 1950) 145, 2494-9. PMID: 2145361 5. Kimura, Y. et al. (1995) International immunology 7, 115-20. PMID: 7718508 6. Demoulin, JB. et al. (1999) The Journal of biological chemistry 274, 25855-61. PMID: 10464327 |
| 备注 | For research use only |
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