| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat |
| 靶标 | Azoreductase, DT-diaphorase, DTD, Dia4, EC:1.6.5.2, Menadione reductase, NAD(P)H dehydrogenase [quinone] 1, NAD(P)H:quinone oxidoreductase 1, Nmo1, Nmor1, Nqo1, Phylloquinone reductase, QR1, Quinone r |
| 免疫原 | E. coli - derived recombinant Mouse NQO1 (Met1-Lys274). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q64669 |
| 背景信息 | NAD(P)H dehydrogenase [quinone] 1 (NQO1) is a ~30 kDa protein. Flavin-containing quinone reductase that catalyzes two-electron reduction of quinones to hydroquinones using either NADH or NADPH as electron donors. In a ping-pong kinetic mechanism, the electrons are sequentially transferred from NAD(P)H to flavin cofactor and then from reduced flavin to the quinone, bypassing the formation of semiquinone and reactive oxygen species. Regulates cellular redox state primarily through quinone detoxification. Reduces components of plasma membrane redox system such as coenzyme Q and vitamin quinones, producing antioxidant hydroquinone forms. In the process may function as superoxide scavenger to prevent hydroquinone oxidation and facilitate excretion. 1. Chen, S. et al. (1997) The Journal of biological chemistry 272, 1437-9. PMID: 8999809 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 8052 |
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| 肝素结合蛋白单克隆抗体 | 7253 |
| CRP单克隆抗体 | 8298 |
| 猫胰脂肪酶单克隆抗体 | 7504 |
| 马SAA单克隆抗体 | 8156 |
| 犬腺病毒单克隆抗体 | 7197 |
| 犬轮状病毒单克隆抗体 | 7308 |
| 犬血红蛋白单克隆抗体 | 8390 |
| 犬胰脂肪酶单克隆抗体 | 7106 |
| 犬松弛素单克隆抗体 | 7532 |
| 犬冠状病毒单克隆抗体 | 7480 |
| 犬瘟病毒单克隆抗体 | 7218 |
| 犬细小病毒单克隆抗体 | 7733 |
| 猫瘟病毒单克隆抗体 | 7885 |
| 猫疱疹病毒单克隆抗体 | 7603 |
| 猫杯状病毒单克隆抗体 | 8077 |
| 猫SAA单克隆抗体 | 7586 |
| 犬CRP单克隆抗体 | 8139 |
| 犬、猫IgG单克隆抗体 | 7441 |