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Anti-Mouse CFB Polyclonal Antibody|抗小鼠CFB多克隆抗体(靶标:小鼠补体因子B)

  • 货号:RB9TMF634014
  • 价格:面议
  • 点击:261

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse
靶标Bf, C3/C5 convertase, Cfb, Complement factor B, Complement factor B Ba, Complement factor B Bb, EC:3.4.21.47, H2-Bf
免疫原E. coli - derived recombinant Mouse CFB (Gly484-Leu761).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P04186
背景信息

Complement factor B (CFB) is a ~85 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases.

备注For research use only
【仅供科学研究使用】

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