Anti-Mouse CFB Polyclonal Antibody|抗小鼠CFB多克隆抗体(靶标：小鼠补体因子B)
- 货号：RB9TMF634014
- 价格：面议
- 点击：438
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | Bf, C3/C5 convertase, Cfb, Complement factor B, Complement factor B Ba, Complement factor B Bb, EC:3.4.21.47, H2-Bf |
| 免疫原 | E. coli - derived recombinant Mouse CFB (Gly484-Leu761). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P04186 |
| 背景信息 | Complement factor B (CFB) is a ~85 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes of the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The alternative complement pathway acts as an amplification loop that enhances other complement pathways (classical, lectin and GZMK) by promoting formation of additional C3 and C5 convertases. CFB is cleaved and activated by CFD to generate Ba and Bb chains; Bb chain constituting the catalytic component of the C3 and C5 convertases. |
| 备注 | For research use only |
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