当前位置：首页>产品中心>单抗/多抗>Anti-Mouse CD350/FZD10 Polyclonal Antibody|抗小鼠CD350/FZD10多克隆抗体(靶标：小鼠卷曲蛋白受体10/CD350)
Anti-Mouse CD350/FZD10 Polyclonal Antibody|抗小鼠CD350/FZD10多克隆抗体(靶标：小鼠卷曲蛋白受体10/CD350)
- 货号：RB9TMV512014
- 价格：面议
- 点击：511
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | CD350, Frizzled-10, Fz-10, Fz10, Fzd10 |
| 免疫原 | E. coli - derived recombinant Mouse CD350/FZD10 (Asn61-Asp143). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8BKG4 |
| 背景信息 | Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. 1. Wang, Z. et al. (2005) Molecular and cellular biology 25, 5022-30. PMID: 15923619 |
| 备注 | For research use only |
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