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Anti-Mouse IL4 Polyclonal Antibody|抗小鼠IL4多克隆抗体(靶标:小鼠白细胞介素4)

  • 货号:RB9TMY457014
  • 价格:面议
  • 点击:255

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse
靶标B-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra
免疫原E. coli - derived recombinant Mouse IL4 (His23-Ser140).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P07750
背景信息

Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.

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2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301
3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964
4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794
5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615
6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241
7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821
备注For research use only
【仅供科学研究使用】

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