| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | B-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra |
| 免疫原 | E. coli - derived recombinant Mouse IL4 (His23-Ser140). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P07750 |
| 背景信息 | Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. 1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412 2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301 3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964 4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794 5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615 6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241 7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7601 |
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| 阿米巴单克隆抗体 | 8086 |
| 胃蛋白酶单克隆抗体 | 7493 |
| 胃蛋白酶原II单克隆抗体 | 7787 |
| 胃蛋白酶原I单克隆抗体 | 7437 |
| 艰难梭菌毒素A单克隆抗体 | 7616 |
| 艰难梭菌毒素B单克隆抗体 | 7986 |
| 艰难梭菌GDH单克隆抗体 | 7900 |
| 诺如病毒单克隆抗体 | 7395 |
| 伤寒沙门氏菌单克隆抗体 | 7467 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6968 |
| 幽门螺杆菌单克隆抗体 | 7520 |
| 钙卫蛋白单克隆抗体 | 7295 |
| 乳铁蛋白单克隆抗体 | 7650 |
| 转铁蛋白单克隆抗体 | 7658 |
| 血红蛋白单克隆抗体 | 7335 |
| 腺病毒单克隆抗体 | 7601 |
| 轮状病毒单克隆抗体 | 8030 |