| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | B-cell stimulatory factor 1, BSF-1, Binetrakin, IL-4, IL4, Interleukin-4, Lymphocyte stimulatory factor 1, Pitrakinra |
| 免疫原 | E. coli - derived recombinant Mouse IL4 (His23-Ser140). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P07750 |
| 背景信息 | Interleukin-4 (IL4) is a ~15 kDa protein. Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1. Also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. 1. Lee, F. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 2061-5. PMID: 3083412 2. Sideras, P. et al. (1987) Advances in experimental medicine and biology 213, 227-36. PMID: 3498301 3. Terawaki, S. et al. (2015) The Journal of cell biology 210, 1133-52. PMID: 26416964 4. Moon, ML. et al. (2015) Behavior genetics 45, 451-60. PMID: 25772794 5. Bogale, TMH. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2681-2688. PMID: 28202615 6. Edukulla, R. et al. (2015) The Journal of biological chemistry 290, 13510-20. PMID: 25847241 7. Kaplan, MH. et al. (1996) Immunity 4, 313-9. PMID: 8624821 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6348 |
| 多菌灵/阿苯达唑二合一单抗 | 6428 |
| 三氯噻嗪单抗 | 6527 |
| 吡唑醚菌酯单抗 | 6767 |
| 烯酰吗啉单抗 | 6610 |
| 抑霉唑单抗 | 6291 |
| 恶醚唑(苯醚甲环唑)单抗 | 6457 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6476 |
| 辛硫磷单抗 | 6561 |
| 多效唑单抗 | 6445 |
| 对硫磷单抗 | 6641 |
| 丙溴磷单抗 | 6693 |
| 戊唑醇单抗 | 6692 |
| 莠去津单抗 | 6552 |
| 灭蝇胺单抗 | 6231 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6501 |
| 2.4-二氯苯氧乙酸单抗 | 6354 |
| 甲基对硫磷单抗 | 6426 |
| 左旋咪唑单抗 | 6376 |
| 三唑磷单抗 | 6461 |