当前位置:首页>产品中心>单抗/多抗>Anti-Mouse IGF1 Polyclonal Antibody|抗小鼠IGF1多克隆抗体(靶标:小鼠胰岛素样生长因子1)

Anti-Mouse IGF1 Polyclonal Antibody|抗小鼠IGF1多克隆抗体(靶标:小鼠胰岛素样生长因子1)

  • 货号:RB9TMY095014
  • 价格:面议
  • 点击:382

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Human, Mouse
靶标IBP1, IGF-1, IGF-I, IGF1, Insulin-like growth factor 1, Insulin-like growth factor I, MGF, Mechano growth factor, Somatomedin-C
免疫原E. coli - derived recombinant Mouse IGF1 (Val65-Lys134).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P05017
背景信息

Insulin-like growth factor 1 (IGF1) is a ~17 kDa protein. The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.

1. Cao, P. et al. (2011) Cell 145, 300-11. PMID: 21496647
备注For research use only
【仅供科学研究使用】

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