| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse |
| 靶标 | (R,R)-butanediol dehydrogenase, EC:1.1.1.-, EC:1.1.1.14, EC:1.1.1.4, EC:1.1.1.56, EC:1.1.1.9, L-iditol 2-dehydrogenase, Polyol dehydrogenase, RDH, Ribitol dehydrogenase, SDH, SORD, Sorbitol dehydrogen |
| 免疫原 | E. coli - derived recombinant Mouse SORD (Met1-Pro357). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q64442 |
| 背景信息 | Sorbitol dehydrogenase (SORD) is a ~38 kDa protein. Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility and protein tyrosine phosphorylation. Has no activity on ethanol. 1. Burnell, JN. et al. (1983) The International journal of biochemistry 15, 507-11. PMID: 6852349 2. Cao, W. et al. (2009) Biology of reproduction 80, 124-33. PMID: 18799757 |
| 备注 | For research use only |