Anti-Mouse OAZ1 Polyclonal Antibody|抗小鼠OAZ1多克隆抗体(靶标：小鼠鸟氨酸脱羧酶抗酶1)

Ornithine decarboxylase antizyme 1 (OAZ1) is a ~25 kDa protein. Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter.