Anti-Human PLCD3 Polyclonal Antibody|抗人PLCD3多克隆抗体(靶标：人磷脂酶Cδ3)

形态	Liquid
宿主种属	Rabbit
克隆性	Polyclonal
抗体亚型	IgG
纯化方式	Purified by antigen affinity column.
内毒素水平	Please contact with the lab for this information.
应用	ELISA, IHC, WB
种属反应性	Mouse, Human
靶标	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, EC:3.1.4.11, KIAA1964, PLC-delta-3, PLCD3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3
免疫原	E. coli - derived recombinant Human PLCD3 (Pro46-Leu251).
储存缓冲液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号	Q8N3E9
背景信息	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (PLCD3) is a ~89 kDa protein. Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow. Regulates neurite outgrowth through the inhibition of RhoA/Rho kinase signaling. 1. Pawelczyk, T. et al. (1999) European journal of biochemistry 262, 291-8. PMID: 10336610
备注	For research use only

【仅供科学研究使用】

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