| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | 70 kDa ribosomal protein S6 kinase 2, EC:2.7.11.1, P70S6K2, RPS6KB2, Ribosomal protein S6 kinase beta-2, S6 kinase-related kinase, S6K-beta, S6K-beta-2, S6K2, SRK, STK14B, Serine/threonine-protein kin |
| 免疫原 | E. coli - derived recombinant Human RPS6KB2 (Arg61-Ser403). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UBS0 |
| 背景信息 | Ribosomal protein S6 kinase beta-2 (RPS6KB2) is a ~53 kDa protein. Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7. 1. Nguyen, JT. et al. (2018) Science advances 4, eaao5838. PMID: 29750193 |
| 备注 | For research use only |