当前位置：首页>产品中心>单抗/多抗>Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody|抗小鼠CD365/KIM-1/TIM-1/HAVCR1多克隆抗体(靶标：小鼠甲型肝炎病毒细胞受体1/KIM-1/TIM-1/CD365)
Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody|抗小鼠CD365/KIM-1/TIM-1/HAVCR1多克隆抗体(靶标：小鼠甲型肝炎病毒细胞受体1/KIM-1/TIM-1/CD365)
- 货号：RB9TMV277014
- 价格：面议
- 点击：552
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | CD365, HAVCR1, HAVcr-1, Hepatitis A virus cellular receptor 1, KIM-1, KIM1, Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell immunoglobulin mucin receptor |
| 免疫原 | E. coli - derived recombinant Mouse CD365/KIM-1/TIM-1/HAVCR1 (Tyr22-Gly237). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q5QNS5 |
| 背景信息 | Hepatitis A virus cellular receptor 1 homolog (CD365/KIM-1) is a ~33 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation. 1. Ding, Q. et al. (2011) The Journal of clinical investigation 121, 3645-56. PMID: 21821911 2. Yeung, MY. et al. (2015) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, 942-53. PMID: 25645598 3. Xiao, S. et al. (2020) Cell reports 32, 107892. PMID: 32668241 4. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780 5. Xiao, S. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 1602-8. PMID: 25582854 6. Meyers, JH. et al. (2005) Nature immunology 6, 455-64. PMID: 15793576 |
| 备注 | For research use only |
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