| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | DHH, DHH-N, Desert hedgehog protein, Desert hedgehog protein N-product, EC:3.1.-.-, HHG-3 |
| 免疫原 | E. coli - derived recombinant Human DHH (Gly202-Gly396). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O43323 |
| 背景信息 | Desert hedgehog protein (DHH) is a ~43 kDa protein. The C-terminal part of the desert hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (N-product and C-product) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product (DHH-N). Both activities occur in the endoplasmic reticulum. Once cleaved, the C-product is degraded in the endoplasmic reticulum. Functions in cell-cell mediated juxtacrine signaling. 1. Pettigrew, CA. et al. (2014) Mechanisms of development 131, 137-49. PMID: 24342078 2. Hollier, PL. et al. (2021) Cardiovascular research 117, 2489-2501. PMID: 33063110 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 痢疾志贺氏菌单克隆抗体 | 7626 |
| 沙门氏菌单克隆抗体 | 7442 |
| 乙型副伤寒沙门氏菌单克隆抗体 | 8012 |
| A族链球菌单克隆抗体 | 7652 |
| 甲型副伤寒沙门氏菌单抗 | 7428 |
| 麻疹病毒单克隆抗体 | 7586 |
| HBeAg单克隆抗体 | 7599 |
| 新型冠状病毒(SARS-COV-2)NP蛋白单克隆抗体 | 7081 |
| 呼吸道腺病毒单克隆抗体 | 7861 |
| 大肠杆菌单克隆抗体 | 7686 |
| LP-PLA2单克隆抗体 | 7670 |
| NT-PROBNP单克隆抗体 | 7370 |
| 半乳糖凝集素3单克隆抗体 | 7380 |
| D二聚体单克隆抗体 | 7439 |
| 肌钙蛋白单克隆抗体 | 7680 |
| 肌红蛋白单克隆抗体 | 7556 |
| AAT单克隆抗体 | 7384 |
| 人SAA单克隆抗体 | 7325 |
| 黏病毒抗性蛋白A单克隆抗体 | 7527 |
| 降钙素原单克隆抗体 | 7242 |