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Anti-Mouse Arl13b Polyclonal Antibody|抗小鼠Arl13b多克隆抗体(靶标:小鼠ADP核糖基化因子样蛋白13B)

  • 货号:RB9TMS942014
  • 价格:面议
  • 点击:521
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse
靶标ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL13B, ARL2-like protein 1, ARL2L1
免疫原E. coli - derived recombinant Mouse Arl13b (Met1-Ser241).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q640N2
背景信息

ADP-ribosylation factor-like protein 13B (Arl13b) is a ~48 kDa protein. Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling.

1. Higginbotham, H. et al. (2013) Nature neuroscience 16, 1000-7. PMID: 23817546
2. Higginbotham, H. et al. (2012) Developmental cell 23, 925-38. PMID: 23153492
备注For research use only
【仅供科学研究使用】

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