Anti-Human ZNF423 Polyclonal Antibody|抗人ZNF423多克隆抗体(靶标：人锌指蛋白423)
- 货号：RB9THS903014
- 价格：面议
- 点击：304
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | KIAA0760, NPHP14, OAZ, Olf1/EBF-associated zinc finger protein, Smad- and Olf-interacting zinc finger protein, ZNF423, Zinc finger protein 423, hOAZ |
| 免疫原 | E. coli - derived recombinant Human ZNF423 (Asp880-Gln1284). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q2M1K9 |
| 背景信息 | Zinc finger protein 423 (ZNF423) is a ~144 kDa protein. Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. |
| 备注 | For research use only |
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