| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | BLOC-2 complex member HPS6, HPS6, Hermansky-Pudlak syndrome 6 protein, Ru, Ruby-eye protein homolog |
| 免疫原 | E. coli - derived recombinant Human HPS6 (Thr6-Gly387). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q86YV9 |
| 背景信息 | BLOC-2 complex member HPS6 is a ~82 kDa protein. May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning. 1. Schreyer-Shafir, N. et al. (2006) Human mutation 27, 1158. PMID: 17041891 2. Li, K. et al. (2014) Journal of cell science 127, 4574-88. PMID: 25189619 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| NGAL单克隆抗体 | 7662 |
| 白细胞介素6(IL-6)单克隆抗体 | 7348 |
| 肝素结合蛋白单克隆抗体 | 6828 |
| CRP单克隆抗体 | 7629 |
| 猫胰脂肪酶单克隆抗体 | 7177 |
| 马SAA单克隆抗体 | 7540 |
| 犬腺病毒单克隆抗体 | 6907 |
| 犬轮状病毒单克隆抗体 | 6986 |
| 犬血红蛋白单克隆抗体 | 7948 |
| 犬胰脂肪酶单克隆抗体 | 6794 |
| 犬松弛素单克隆抗体 | 7164 |
| 犬冠状病毒单克隆抗体 | 7174 |
| 犬瘟病毒单克隆抗体 | 6884 |
| 犬细小病毒单克隆抗体 | 7343 |
| 猫瘟病毒单克隆抗体 | 7445 |
| 猫疱疹病毒单克隆抗体 | 7211 |
| 猫杯状病毒单克隆抗体 | 7631 |
| 猫SAA单克隆抗体 | 7276 |
| 犬CRP单克隆抗体 | 7809 |
| 犬、猫IgG单克隆抗体 | 7159 |