| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | CAVIN1, Caveolae-associated protein 1, Cavin-1, PTRF, Polymerase I and transcript release factor |
| 免疫原 | E. coli - derived recombinant Human CAVIN1 (Leu43-Val153). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q6NZI2 |
| 背景信息 | Caveolae-associated protein 1 (CAVIN1) is a ~43 kDa protein. Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. Core component of the CAVIN complex which is essential for recruitment of the complex to the caveolae in presence of calveolin-1 (CAV1). Essential for normal oligomerization of CAV1. Promotes ribosomal transcriptional activity in response to metabolic challenges in the adipocytes and plays an important role in the formation of the ribosomal transcriptional loop. 1. Liu, L. et al. (2008) The Journal of biological chemistry 283, 4314-22. PMID: 18056712 2. Hill, MM. et al. (2008) Cell 132, 113-24. PMID: 18191225 3. Hayashi, YK. et al. (2009) The Journal of clinical investigation 119, 2623-33. PMID: 19726876 |
| 备注 | For research use only |