| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | NAG-2, NAG2, Novel antigen 2, TM4SF7, TSPAN4, Tetraspanin-4, Transmembrane 4 superfamily member 7, Tspan-4 |
| 免疫原 | E. coli - derived recombinant Human TSPAN4 (Tyr107-Asn201). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O14817 |
| 背景信息 | Tetraspanin-4 (TSPAN4) is a ~26 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays an essential role in migrasome formation and migration on retracting fibers at the rear end of migrating cells. Migrasomes are cellular organelles that form as large vesicle-like structures on retraction fibers of migrating cells. Mechanistically, acts as a membrane curvature sensor and participates in stabilizing the migrasome structure in a late stage of biogenesis. May also play a regulatory role for the histamine H4 receptor/HRH4 without affecting histamine binding to HRH4 or signaling. 1. Huang, Y. et al. (2019) Nature cell biology 21, 991-1002. PMID: 31371828 2. Dharan, R. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2208993119. PMID: 36252000 3. Dharan, R. et al. (2023) Nature communications 14, 1037. PMID: 36823145 4. Ma, X. et al. (2021) Biomolecules 11. PMID: 34439793 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5716 |
| 西马特罗单抗 | 5695 |
| 孕酮单抗 | 5889 |
| 氯霉素(CAP)单抗 | 5825 |
| 红霉素单抗 | 5792 |
| 地克珠利单抗 | 5605 |
| 无色孔雀石绿(LMG)单抗 | 5827 |
| 雌二醇单抗 | 5445 |
| 孔雀石绿(MG)单抗 | 5982 |
| 双酚A单抗 | 5757 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5626 |
| 己烯雌酚单抗 | 5631 |
| 莱克多巴胺(RAC)单抗 | 5795 |
| 林可霉素单抗 | 5986 |
| 抗青霉素受体单抗 | 5628 |
| 大观霉素单抗 | 5687 |
| 克伦特罗(CL)单抗 | 5903 |
| 沙拉沙星单抗(2H4) | 5716 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5885 |
| 磺胺类SAS单抗 | 5827 |