Anti-Human DUSP29 Polyclonal Antibody|抗人DUSP29多克隆抗体(靶标：人双特异性磷酸酶29)
- 货号：RB9THD314014
- 价格：面议
- 点击：514
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | DUPD1, DUSP27, DUSP29, Dual specificity phosphatase 27, Dual specificity phosphatase 29, Dual specificity phosphatase DUPD1, EC:3.1.3.16, EC:3.1.3.48 |
| 免疫原 | E. coli - derived recombinant Human DUSP29 (Thr35-Leu220). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q68J44 |
| 背景信息 | Dual specificity phosphatase 29 (DUSP29) is a ~25 kDa protein. Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate. Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase. Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy. 1. Friedberg, I. et al. (2007) FEBS letters 581, 2527-33. PMID: 17498703 |
| 备注 | For research use only |
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