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Anti-Human UTP25 Polyclonal Antibody|抗人UTP25多克隆抗体(靶标:人UTP25小亚基加工体组分)

  • 货号:RB9THD313014
  • 价格:面议
  • 点击:350

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标C1orf107, DEF, DIEXF, Digestive organ expansion factor homolog, U3 small nucleolar RNA-associated protein 25 homolog, UTP25, UTP25 small subunit processor component
免疫原E. coli - derived recombinant Human UTP25 (Asn180-Asn561).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q68CQ4
背景信息

U3 small nucleolar RNA-associated protein 25 homolog (UTP25) is a ~87 kDa protein. Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing. Essential for embryonic development in part through the regulation of p53 pathway. Controls the expansion growth of digestive organs and liver. Also involved in the sympathetic neuronal development. Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53.

1. Tao, T. et al. (2013) Cell research 23, 620-34. PMID: 23357851
2. Lei, H. et al. (2014) BMC gastroenterology 14, 123. PMID: 25007945
3. Guan, Y. et al. (2016) PLoS biology 14, e1002555. PMID: 27657329
备注For research use only
【仅供科学研究使用】

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