当前位置:首页>产品中心>单抗/多抗>Anti-Human TSHZ3 Polyclonal Antibody|抗人TSHZ3多克隆抗体(靶标:人Teashirt锌指同源盒蛋白3)

Anti-Human TSHZ3 Polyclonal Antibody|抗人TSHZ3多克隆抗体(靶标:人Teashirt锌指同源盒蛋白3)

  • 货号:RB9THD311014
  • 价格:面议
  • 点击:493

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse, Rat
靶标KIAA1474, TSH3, TSHZ3, Teashirt homolog 3, ZNF537, Zinc finger protein 537
免疫原E. coli - derived recombinant Human TSHZ3 (Trp898-Gln1081).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q63HK5
背景信息

Teashirt homolog 3 (TSHZ3) is a ~118 kDa protein. Transcriptional regulator involved in developmental processes. Functions in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). Regulates the development of neurons involved in both respiratory rhythm and airflow control.

1. Kajiwara, Y. et al. (2009) PloS one 4, e5071. PMID: 19343227
备注For research use only
【仅供科学研究使用】

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