当前位置:首页>产品中心>单抗/多抗>Anti-Human TRMT5 Polyclonal Antibody|抗人TRMT5多克隆抗体(靶标:人tRNA甲基转移酶5)

Anti-Human TRMT5 Polyclonal Antibody|抗人TRMT5多克隆抗体(靶标:人tRNA甲基转移酶5)

  • 货号:RB9THD270014
  • 价格:面议
  • 点击:522

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标EC:2.1.1.228, KIAA1393, M1G-methyltransferase, TRM5, TRMT5, tRNA (guanine(37)-N(1))-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog
免疫原E. coli - derived recombinant Human TRMT5 (Thr65-Lys475).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q32P41
背景信息

tRNA (guanine(37)-N(1))-methyltransferase (TRMT5) is a ~58 kDa protein. Involved in mitochondrial tRNA methylation. Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

1. Powell, CA. et al. (2015) American journal of human genetics 97, 319-28. PMID: 26189817
备注For research use only
【仅供科学研究使用】

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