| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | ZNF827, Zinc finger protein 827 |
| 免疫原 | E. coli - derived recombinant Human ZNF827 (Ser809-Gly954). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q17R98 |
| 背景信息 | Zinc finger protein 827 (ZNF827) is a ~119 kDa protein. As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation. Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance. 1. Hollensen, AK. et al. (2020) eLife 9. PMID: 33174841 2. Conomos, D. et al. (2014) Nature structural & molecular biology 21, 760-70. PMID: 25150861 |
| 备注 | For research use only |