| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | TAF(II)100, TAF2D, TAF5, TAFII-100, TAFII100, Transcription initiation factor TFIID 100 kDa subunit, Transcription initiation factor TFIID subunit 5 |
| 免疫原 | E. coli - derived recombinant Human TAF5 (Leu458-Gln800). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q15542 |
| 背景信息 | Transcription initiation factor TFIID subunit 5 (TAF5) is a ~86 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Dubrovskaya, V. et al. (1996) The EMBO journal 15, 3702-12. PMID: 8758937 3. Tanese, N. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 13611-6. PMID: 8942982 4. Tao, Y. et al. (1997) The Journal of biological chemistry 272, 6714-21. PMID: 9045704 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5515 |
| 金刚烷胺单抗 | 5568 |
| 卡那霉素单抗 | 5722 |
| 黄曲霉毒素M1(AFM1)单抗 | 5689 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5870 |
| 帕托珠利(妥曲珠利砜)单抗 | 5595 |
| 泰乐菌素单抗 | 5642 |
| 替米考星单抗 | 5749 |
| 新霉素单抗 | 5747 |
| 安普霉素单抗 | 5679 |
| 三聚氰胺(MEL)单抗 | 5595 |
| 双氟沙星单抗 | 5544 |
| 西地那非单抗 | 5664 |
| 阿苯达唑单抗 | 5451 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5619 |
| 氟苯尼考单抗 | 5655 |
| 诺龙单抗 | 5726 |
| 达氟沙星单抗 | 5845 |
| 培氟沙星单抗 | 5707 |
| 庆大霉素单抗 | 5852 |