| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | TAF(II)100, TAF2D, TAF5, TAFII-100, TAFII100, Transcription initiation factor TFIID 100 kDa subunit, Transcription initiation factor TFIID subunit 5 |
| 免疫原 | E. coli - derived recombinant Human TAF5 (Leu458-Gln800). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q15542 |
| 背景信息 | Transcription initiation factor TFIID subunit 5 (TAF5) is a ~86 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C. TAF5 is involved in two modules of TFIID, in TFIID-A together with TAF3 and TBP, and in TFIID-B with TAF8. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Dubrovskaya, V. et al. (1996) The EMBO journal 15, 3702-12. PMID: 8758937 3. Tanese, N. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 13611-6. PMID: 8942982 4. Tao, Y. et al. (1997) The Journal of biological chemistry 272, 6714-21. PMID: 9045704 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7523 |
| 人触珠蛋白单克隆抗体 | 7725 |
| 贾第鞭毛虫单克隆抗体 | 7372 |
| 阿米巴单克隆抗体 | 7906 |
| 胃蛋白酶单克隆抗体 | 7407 |
| 胃蛋白酶原II单克隆抗体 | 7603 |
| 胃蛋白酶原I单克隆抗体 | 7326 |
| 艰难梭菌毒素A单克隆抗体 | 7488 |
| 艰难梭菌毒素B单克隆抗体 | 7781 |
| 艰难梭菌GDH单克隆抗体 | 7779 |
| 诺如病毒单克隆抗体 | 7275 |
| 伤寒沙门氏菌单克隆抗体 | 7368 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6872 |
| 幽门螺杆菌单克隆抗体 | 7383 |
| 钙卫蛋白单克隆抗体 | 7150 |
| 乳铁蛋白单克隆抗体 | 7514 |
| 转铁蛋白单克隆抗体 | 7516 |
| 血红蛋白单克隆抗体 | 7233 |
| 腺病毒单克隆抗体 | 7460 |
| 轮状病毒单克隆抗体 | 7847 |