| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | EC:3.6.5.2, RAB32, Ras-related protein Rab-32 |
| 免疫原 | E. coli - derived recombinant Human RAB32 (Met1-Cys225). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13637 |
| 背景信息 | Ras-related protein Rab-32 (RAB32) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Also acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. 1. Bao, X. et al. (2002) European journal of biochemistry 269, 259-71. PMID: 11784320 2. Nottingham, RM. et al. (2011) The Journal of biological chemistry 286, 33213-22. PMID: 21808068 3. Alto, NM. et al. (2002) The Journal of cell biology 158, 659-68. PMID: 12186851 4. Seto, S. et al. (2011) Traffic (Copenhagen, Denmark) 12, 407-20. PMID: 21255211 5. Gerondopoulos, A. et al. (2012) Current biology : CB 22, 2135-9. PMID: 23084991 6. Zhu, H. et al. (2023) Science (New York, N.Y.) 382, 1404-1411. PMID: 38127736 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6307 |
| 多菌灵/阿苯达唑二合一单抗 | 6380 |
| 三氯噻嗪单抗 | 6472 |
| 吡唑醚菌酯单抗 | 6691 |
| 烯酰吗啉单抗 | 6510 |
| 抑霉唑单抗 | 6239 |
| 恶醚唑(苯醚甲环唑)单抗 | 6410 |
| 赛拉嗪(甲苯噻嗪)单抗 | 6425 |
| 辛硫磷单抗 | 6506 |
| 多效唑单抗 | 6372 |
| 对硫磷单抗 | 6570 |
| 丙溴磷单抗 | 6613 |
| 戊唑醇单抗 | 6610 |
| 莠去津单抗 | 6485 |
| 灭蝇胺单抗 | 6178 |
| 尼卡巴嗪代谢物(DNC)单抗 | 6466 |
| 2.4-二氯苯氧乙酸单抗 | 6312 |
| 甲基对硫磷单抗 | 6390 |
| 左旋咪唑单抗 | 6325 |
| 三唑磷单抗 | 6400 |