| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, BNIP1, NIP1, SEC20L, TRG-8, Transformation-related gene 8 protein, Vesicle transport protein SEC20 |
| 免疫原 | E. coli - derived recombinant Human BNIP1 (Met1-Leu199). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q12981 |
| 背景信息 | Vesicle transport protein SEC20 (BNIP1) is a ~26 kDa protein. As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Also plays a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable). 1. Nakajima, K. et al. (2004) The EMBO journal 23, 3216-26. PMID: 15272311 2. Wang, P. et al. (2013) Cellular signalling 25, 2320-33. PMID: 23896122 3. Boyd, JM. et al. (1994) Cell 79, 341-51. PMID: 7954800 |
| 备注 | For research use only |