| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | BNC, BNC1, Zinc finger protein basonuclin-1 |
| 免疫原 | E. coli - derived recombinant Human BNC1 (Thr38-Asn250). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q01954 |
| 背景信息 | Zinc finger protein basonuclin-1 (BNC1) is a ~110 kDa protein. Transcriptional activator. It is likely involved in the regulation of keratinocytes terminal differentiation in squamous epithelia and hair follicles. Required for the maintenance of spermatogenesis. It is involved in the positive regulation of oocyte maturation, probably acting through the control of BMP15 levels and regulation of AKT signaling cascade. May also play a role in the early development of embryos. 1. Tseng, H. et al. (1994) The Journal of cell biology 126, 495-506. PMID: 8034748 2. Zhang, D. et al. (2018) Human molecular genetics 27, 3787-3800. PMID: 30010909 |
| 备注 | For research use only |