| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | FOE, Friend of EBNA2 protein, KIAA0261, WAPAL, WAPL, WAPL cohesin release factor, Wings apart-like protein homolog |
| 免疫原 | E. coli - derived recombinant Human WAPL (His641-Asp838). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q7Z5K2 |
| 背景信息 | Wings apart-like protein homolog (WAPL) is a ~132 kDa protein. Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. 1. Yeh, C. et al. (2015) Current biology : CB 25, 2290-9. PMID: 26299517 |
| 备注 | For research use only |