Anti-Human UBE2G2 Polyclonal Antibody|抗人UBE2G2多克隆抗体(靶标：人泛素结合酶E2G2)
- 货号：RB9THD110014
- 价格：面议
- 点击：605
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | E2 ubiquitin-conjugating enzyme G2, EC:2.3.2.23, UBC7, UBE2G2, Ubiquitin carrier protein G2, Ubiquitin-conjugating enzyme E2 G2, Ubiquitin-protein ligase G2 |
| 免疫原 | E. coli - derived recombinant Human UBE2G2 (Met1-Leu165). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P60604 |
| 背景信息 | Ubiquitin-conjugating enzyme E2 G2 (UBE2G2) is a ~18 kDa protein. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation. 1. David, Y. et al. (2010) The Journal of biological chemistry 285, 8595-604. PMID: 20061386 2. Sato, T. et al. (2012) Molecular cell 47, 99-110. PMID: 22607976 3. Jo, Y. et al. (2013) Molecular biology of the cell 24, 169-83. PMID: 23223569 |
| 备注 | For research use only |
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