Anti-Human RRAD Polyclonal Antibody|抗人RRAD多克隆抗体(靶标：人Ras相关糖蛋白Rad)
- 货号：RB9THD074014
- 价格：面议
- 点击：817
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Rat, Mouse, Human |
| 靶标 | GTP-binding protein RAD, RAD, RAD1, RRAD, Ras associated with diabetes |
| 免疫原 | E. coli - derived recombinant Human RRAD (Val91-Leu308). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P55042 |
| 背景信息 | GTP-binding protein RAD (RRAD) is a ~33 kDa protein. May regulate basal voltage-dependent L-type Ca(2+) currents and be required for beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D. 1. Chang, L. et al. (2007) Circulation 116, 2976-2983. PMID: 18056528 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 6320 |
| 金刚烷胺单抗 | 6545 |
| 卡那霉素单抗 | 6539 |
| 黄曲霉毒素M1（AFM1）单抗 | 6490 |
| 群勃龙（孕三烯酮）（去甲雄三烯醇酮）单抗 | 7464 |
| 帕托珠利（妥曲珠利砜）单抗 | 6427 |
| 泰乐菌素单抗 | 6547 |
| 替米考星单抗 | 6439 |
| 新霉素单抗 | 6749 |
| 安普霉素单抗 | 6612 |
| 三聚氰胺（MEL）单抗 | 6561 |
| 双氟沙星单抗 | 6440 |
| 西地那非单抗 | 6511 |
| 阿苯达唑单抗 | 6409 |
| 醋酸甲羟孕酮（醋酸甲孕酮）单抗 | 6518 |
| 氟苯尼考单抗 | 6591 |
| 诺龙单抗 | 6629 |
| 达氟沙星单抗 | 6736 |
| 培氟沙星单抗 | 6573 |
| 庆大霉素单抗 | 6653 |
