Anti-Human SLURP2 Polyclonal Antibody|抗人SLURP2多克隆抗体(靶标：人SLURP2蛋白)
- 货号：RB9THC987014
- 价格：面议
- 点击：382
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | SLURP-2, SLURP2, Secreted LY6/PLAUR domain-containing protein 2, Secreted Ly-6/uPAR domain-containing protein 2, Secreted Ly-6/uPAR-related protein 2 |
| 免疫原 | E. coli - derived recombinant Human SLURP2 (Ile23-Asp97). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P0DP57 |
| 背景信息 | Secreted Ly-6/uPAR domain-containing protein 2 (SLURP2) is a ~10 kDa protein. Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modulates alpha-7-containing nAChRs, and inhibits nicotine-induced signaling probably implicating alpha-3:beta-4-containing nAChRs. Proposed to act on alpha-3:beta-2 and alpha-7 nAChRs in an orthosteric, and on mAChRs, such as CHRM1 and CHRM3, in an allosteric manner. |
| 备注 | For research use only |
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