| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | G17, N-system amino acid transporter 1, NAT1, Na(+)-coupled neutral amino acid transporter 3, SLC38A3, SN1, SNAT3, Sodium-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, S |
| 免疫原 | E. coli - derived recombinant Human SLC38A3 (Lys234-Asn323). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q99624 |
| 背景信息 | Sodium-coupled neutral amino acid transporter 3 (SLC38A3) is a ~55 kDa protein. Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from astrocytes in the intercellular space for the replenishment of both neurotransmitters glutamate and gamma-aminobutyric acid (GABA) in neurons and also functions as the major influx transporter in ganglion cells mediating the uptake of glutamine. The transport activity is specific for L-glutamine, L-histidine and L-asparagine. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). The transport is pH dependent, saturable, Li(+) tolerant and functions in both direction depending on the concentration gradients of its substrates and cotransported ions. 1. Fei, YJ. et al. (2000) The Journal of biological chemistry 275, 23707-17. PMID: 10823827 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 通用型抗体标记物保存液 | 7228 |
| HRP标记抗体保存液 | 7391 |
| Biotin标记抗体保存液 | 7926 |
| FITC标记抗体保存液 | 7621 |
| Myc鼠单抗标签 | 7502 |
| HRP-Myc鼠单抗标签 | 7608 |
| Flag鼠单抗标签 | 7875 |
| HRP-Flag鼠单抗标签 | 7461 |
| GFP鼠单抗标签 | 7468 |
| HRP-GFP鼠单抗标签 | 7487 |
| GST鼠单抗标签 | 7443 |
| HRP-GST鼠单抗标签 | 7399 |
| HA鼠单抗标签 | 8065 |
| HRP-HA鼠单抗标签 | 7707 |
| His鼠单抗标签 | 7440 |
| HRP-His鼠单抗标签 | 7514 |
| MBP鼠单抗标签 | 7424 |
| HRP-MBP鼠单抗标签 | 7688 |
| mCherry鼠单抗标签 | 7259 |
| RFP-鼠单抗标签 | 7590 |