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Anti-Human PRKX Polyclonal Antibody|抗人PRKX多克隆抗体(靶标:人蛋白激酶X连锁)

  • 货号:RB9THC777014
  • 价格:面议
  • 点击:478

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标EC:2.7.11.1, PKX1, PRKX, PrKX, Protein kinase PKX1, Protein kinase X, Protein kinase X-linked, Serine/threonine-protein kinase PRKX, cAMP-dependent protein kinase catalytic subunit PRKX
免疫原E. coli - derived recombinant Human PRKX (Ser45-Arg301).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P51817
背景信息

cAMP-dependent protein kinase catalytic subunit PRKX is a ~40 kDa protein. Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.

备注For research use only
【仅供科学研究使用】

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