| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | INT4, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, WNT3 |
| 免疫原 | E. coli - derived recombinant Human WNT3 (Gly50-Lys355). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P56703 |
| 背景信息 | Proto-oncogene Wnt-3 (WNT3) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge. Required for normal embryonic development, and especially for limb development. 1. Mihara, E. et al. (2016) eLife 5. PMID: 26902720 2. Niemann, S. et al. (2004) American journal of human genetics 74, 558-63. PMID: 14872406 |
| 备注 | For research use only |