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Anti-Human WNT3 Polyclonal Antibody|抗人WNT3多克隆抗体(靶标:人无翅型MMTV整合位点家族成员3)

  • 货号:RB9THC749014
  • 价格:面议
  • 点击:496

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse
靶标INT4, Proto-oncogene Int-4 homolog, Proto-oncogene Wnt-3, WNT3
免疫原E. coli - derived recombinant Human WNT3 (Gly50-Lys355).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P56703
背景信息

Proto-oncogene Wnt-3 (WNT3) is a ~39 kDa protein. Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis. Required for normal formation of the apical ectodermal ridge. Required for normal embryonic development, and especially for limb development.

1. Mihara, E. et al. (2016) eLife 5. PMID: 26902720
2. Niemann, S. et al. (2004) American journal of human genetics 74, 558-63. PMID: 14872406
备注For research use only
【仅供科学研究使用】

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