| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | 40S ribosomal protein S27, MPS-1, MPS1, Metallopan-stimulin 1, RPS27, Small ribosomal subunit protein eS27 |
| 免疫原 | E. coli - derived recombinant Human RPS27 (Ser11-His84). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P42677 |
| 背景信息 | Small ribosomal subunit protein eS27 (RPS27) is a ~9 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Vladimirov, SN. et al. (1996) European journal of biochemistry 239, 144-9. PMID: 8706699 3. Wang, R. et al. (2015) British journal of haematology 168, 854-64. PMID: 25424902 4. Singh, S. et al. (2021) Science (New York, N.Y.) 373, eabj5338. PMID: 34516797 |
| 备注 | For research use only |