| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, EC:3.1.1.47, Group-VIIA phospholipase A2, LDL-PLA(2), LDL-associated phospholipase A2, PAF 2-acylhydrola |
| 免疫原 | E. coli - derived recombinant Mouse LpPLA2/PLA2G7/PAF-AH (Phe22-Asn440). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q60963 |
| 背景信息 | Platelet-activating factor acetylhydrolase (LpPLA2/PLA2G7) is a ~49 kDa protein. Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response. At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position. Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells. 1. Stafforini, DM. et al. (1999) The Journal of biological chemistry 274, 7018-24. PMID: 10066756 2. Gardner, AA. et al. (2008) The Journal of biological chemistry 283, 17099-106. PMID: 18434304 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 痢疾志贺氏菌单克隆抗体 | 7556 |
| 沙门氏菌单克隆抗体 | 7344 |
| 乙型副伤寒沙门氏菌单克隆抗体 | 7910 |
| A族链球菌单克隆抗体 | 7504 |
| 甲型副伤寒沙门氏菌单抗 | 7285 |
| 麻疹病毒单克隆抗体 | 7516 |
| HBeAg单克隆抗体 | 7493 |
| 新型冠状病毒(SARS-COV-2)NP蛋白单克隆抗体 | 6994 |
| 呼吸道腺病毒单克隆抗体 | 7702 |
| 大肠杆菌单克隆抗体 | 7595 |
| LP-PLA2单克隆抗体 | 7552 |
| NT-PROBNP单克隆抗体 | 7310 |
| 半乳糖凝集素3单克隆抗体 | 7283 |
| D二聚体单克隆抗体 | 7298 |
| 肌钙蛋白单克隆抗体 | 7597 |
| 肌红蛋白单克隆抗体 | 7468 |
| AAT单克隆抗体 | 7266 |
| 人SAA单克隆抗体 | 7237 |
| 黏病毒抗性蛋白A单克隆抗体 | 7466 |
| 降钙素原单克隆抗体 | 7180 |