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Anti-Human FUT1 Polyclonal Antibody|抗人FUT1多克隆抗体(靶标:人岩藻糖基转移酶1/H血型)

  • 货号:RB9THB940014
  • 价格:面议
  • 点击:470

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标Alpha(1,2)FT 1, Blood group H alpha 2-fucosyltransferase, EC:2.4.1.344, EC:2.4.1.69, FUT1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Galactoside alpha-(1,2)
免疫原E. coli - derived recombinant Human FUT1 (Thr80-Pro365).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P19526
背景信息

Galactoside alpha-(1,2)-fucosyltransferase 1 (FUT1) is a ~41 kDa protein. Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a.

1. Larsen, RD. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 6674-8. PMID: 2118655
2. Moehler, TM. et al. (2008) Journal of cellular physiology 215, 27-36. PMID: 18205178
备注For research use only
【仅供科学研究使用】

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