Anti-Human TACR2 Polyclonal Antibody|抗人TACR2多克隆抗体(靶标：人速激肽受体2/NK2R)
- 货号：RB9THB728034
- 价格：面议
- 点击：636
产品介绍
{, "description": "0", "form": "Liquid", "host_species": "Rabbit", "clonality": "Polyclonal", "isotype": "IgG", "purification": "Purified by antigen affinity column.", "endotoxin_level": "Please contact with the lab for this information.", "applications": "ELISA, IHC, WB", "species_reactivity": "Human", "target": "NK-2 receptor, NK-2R, NK2R, NKNAR, Neurokinin A receptor, SKR, Substance-K receptor, TAC2R, TACR2, Tachykinin receptor 2", "immunogen": "E. coli - derived recombinant Human TACR2 (Asn311-Asp362).", "storage_buffer": "0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.", "product_usage_info": "ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000", "accession": "P21452", "background": "Substance-K receptor (TACR2) is a ~44 kDa protein. This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). Is also able to bind and respond to tachynins substance P and neurokinin B/neuromedin-K. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. Substance K binding to its receptor triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C. Substance K binding also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP).
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4. Sun, W. et al. (2022) Cell discovery 8, 72. PMID: 35882833
", "note": "For research use only"}
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