当前位置:首页>产品中心>单抗/多抗>Anti-Human NOCT Polyclonal Antibody|抗人NOCT多克隆抗体(靶标:人夜蛋白/Nocturnin)

Anti-Human NOCT Polyclonal Antibody|抗人NOCT多克隆抗体(靶标:人夜蛋白/Nocturnin)

  • 货号:RB9THA929014
  • 价格:面议
  • 点击:446
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Rat, Human
靶标CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin
免疫原E. coli - derived recombinant Human NOCT (Thr120-Ser431).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9UK39
背景信息

Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis.

1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539
2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338
备注For research use only
【仅供科学研究使用】

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