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Anti-galactose-deficient IgA1 Recombinant Antibody|抗半乳糖缺陷型IgA1重组抗体(靶标:半乳糖缺陷型IgA1)

  • 货号:RB9THV621013
  • 价格:面议
  • 点击:257

产品介绍

产品参数

形态Liquid
宿主种属Rat
克隆性Monoclonal
抗体亚型IgG2b, kappa
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
内毒素水平Please contact with the lab for this information.
应用ELISA, IF, IHC
种属反应性Homo sapiens (Human)
靶标galactose-deficient IgA1, Gd-IgA1, IGHA1, Ig alpha-1 chain C region, Ig alpha-1 chain C region BUR, Ig alpha-1 chain C region TRO, Immunoglobulin heavy constant alpha 1
储存缓冲液0.01M PBS pH 7.4
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重构方法Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
登录号P01876
背景信息

Immunoglobulin heavy constant alpha 1 (Gd-IgA1) is a ~42 kDa protein. Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.

1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268
2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
4. Kerr, MA. (1990) The Biochemical journal 271, 285-96. PMID: 2241915
备注For research use only
【仅供科学研究使用】

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