Anti-G protein/Gαβγ Recombinant Antibody|抗G蛋白/Gαβγ重组抗体(靶标：G蛋白αβγ异源三聚体)
- 货号：RB9THX948023
- 价格：面议
- 点击：507
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 克隆性 | Monoclonal |
| 抗体亚型 | scFv-His |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | Crystallography, Cryo-EM |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | Adenylate cyclase-stimulating G alpha protein, EC:3.6.5.-, GNAS, GNAS1, GSP, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重构方法 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 登录号 | P63092 |
| 背景信息 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gαβγ) is a ~45 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. 1. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 2. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 3. Thiele, S. et al. (2011) Human mutation 32, 653-60. PMID: 21488135 4. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 5. Farfel, Z. et al. (1996) The Journal of biological chemistry 271, 19653-5. PMID: 8702665 6. Warner, DR. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 4268-72. PMID: 10200251 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 过氧化物酶（HRP）标莱克多巴胺单克隆抗体 | 5804 |
| 过氧化物酶（HRP）标沙丁胺醇单克隆抗体 | 5775 |
| 呋喃唑酮代谢物（2-NPAOZ）单抗 | 6249 |
| 环丙沙星（CPFX）单抗 | 5695 |
| 氟喹诺酮类单抗 | 5788 |
| 恩诺沙星单抗 | 5658 |
| 环丙沙星|恩诺沙星|诺氟沙星三合一单抗 | 5759 |
| 睾酮单抗 | 5684 |
| 过氧化物酶（HRP）标睾酮单克隆抗体 | 5567 |
| 过氧化物酶（HRP）标雌三醇单克隆抗体 | 5826 |
| 过氧化物酶（HRP）标记甲基睾酮单克隆抗体 | 6034 |
| 黄曲霉毒素抗体（黄曲霉毒素B1，黄曲霉毒素总量单克隆抗体） | 5628 |
| 苏丹红1号单抗 | 5945 |
| 呋喃西林代谢物（2-NPSEM）单抗（40F11细胞株） | 5544 |
| 小鼠单克隆抗体Ig类/亚类鉴定ELISA试剂盒 | 6434 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定ELISA试剂盒 | 6710 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定酶标二抗即用套装 | 6611 |
| HRP标记小鼠单抗专用稀释液 | 6654 |
| 小鼠单抗腹水制备专用佐剂套装 | 6707 |
| 新冠病毒S蛋白中和抗体ELISA检测试剂盒 | 6463 |